Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.58 |
| ▸ | CTSB | P07858 | 13/20 | 0.58 |
| ▸ | CTSS | P25774 | 12/20 | 0.58 |
| ▸ | CTSK | P43235 | 7/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699482 | 0.82 | CTSL (0.68) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4699742 | 0.81 | CTSL (0.67) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4698845 | 0.79 | CTSL (0.75) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6231955 | 0.73 | CTSB (0.47) | CTSLCTSBCTSSCTSKBACE1 | |
| SCHEMBL4699306 | 0.72 | CTSL (0.60) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4576245 | 0.70 | CTSL (0.94) | CTSLCTSBCTSSCTSK | |
| SCHEMBL2156467 | 0.70 | CTSK (1.00) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6239203 | 0.69 | CTSB (0.47) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4699068 | 0.69 | CTSL (0.66) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4715829 | 0.67 | CTSL (0.62) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372655-A4 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2005-10-12 | — | — | EP | claimed |
| EP-1372655-A2 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | Merck Frosst Canada & Co. (CA) | 2004-01-02 | — | — | EP | claimed |
| WO-2002069901-A2 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2002-09-12 | — | — | WO | claimed |