Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 15/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230537 | 0.88 | BCHE (0.52) | BCHEMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6232919 | 0.85 | PTPRZ1 (0.44) | BCHEMEN1KMT2ANPSR1 | |
| SCHEMBL6240567 | 0.85 | BCHE (0.64) | BCHEMEN1KMT2AMAPK1 | |
| SCHEMBL6231785 | 0.83 | SMN1; SMN2 (0.39) | MEN1KMT2ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL6233694 | 0.81 | SMN1; SMN2 (0.53) | BCHEMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6233779 | 0.79 | CD274 (0.49) | BCHEMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6236427 | 0.78 | MAOB (0.46) | BCHEMEN1KMT2AS1PR1PRKX | |
| SCHEMBL6233816 | 0.77 | SLC2A1 (0.51) | BCHEMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6235445 | 0.76 | SMN1; SMN2 (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6235980 | 0.76 | SMN1; SMN2 (0.59) | BCHEMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |