Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPRB | P23467 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235771 | 0.92 | ESR1 (0.40) | BCL2BCL2L1MCL1BCL2L2MEN1 | |
| SCHEMBL6231787 | 0.83 | TSHR (0.41) | BCL2BCL2L1MCL1BCL2L2MEN1 | |
| SCHEMBL6233833 | 0.80 | KMT2A (0.36) | MEN1KMT2AALDH1A1MAPTPTPRC | |
| SCHEMBL5590500 | 0.79 | LTA4H (0.34) | KMT2APTPRCPTPN2PTPN1PTPRB | |
| SCHEMBL16575430 | 0.75 | MEN1 (0.38) | MEN1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL6232977 | 0.75 | ALOX5 (0.48) | MEN1KMT2AALOX5 | |
| SCHEMBL6258842 | 0.74 | PTGS1 (0.37) | MEN1KMT2AALOX5ALDH1A1HTT | |
| SCHEMBL6233829 | 0.74 | CA12 (0.43) | MEN1KMT2AALDH1A1PTPN11GAA | |
| SCHEMBL5588576 | 0.73 | TP53 (0.41) | MEN1KMT2AALDH1A1MAPTPTPN1 | |
| SCHEMBL6233674 | 0.73 | ALOX5 (0.56) | MEN1KMT2AALOX5HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |