Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PTPRB | P23467 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235777 | 0.93 | THRA (0.38) | TP53RXRAPPARGRARGRXRB | |
| SCHEMBL6231795 | 0.86 | TSHR (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6233828 | 0.80 | BCL2 (0.35) | KMT2AMEN1TP53RXRAPPARG | |
| SCHEMBL6232980 | 0.80 | CYSLTR2 (0.40) | KMT2AMEN1TP53PPARGMAPT | |
| SCHEMBL5586579 | 0.79 | RXRA (0.33) | RXRAPPARGRARGKDM4EPTPRC | |
| SCHEMBL6258847 | 0.78 | KMT2A (0.36) | KMT2AMEN1TP53RXRAPPARG | |
| SCHEMBL5586857 | 0.77 | RXRA (0.39) | KMT2AMEN1TP53RXRAPPARG | |
| SCHEMBL6233682 | 0.77 | ALOX5 (0.40) | KMT2AMEN1TP53 | |
| SCHEMBL5588020 | 0.76 | THRA (0.43) | ALDH1A1PTPN11AKR1C3 | |
| SCHEMBL6236994 | 0.76 | TPMT (0.41) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |