SCHEMBL6234530

SCHEMBL6234530

O=[N+]([O-])c1ccc(C2C3CC4CC(C3)CC2C4)nc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42
MAPT P10636 5/20 0.42
ALDH1A1 P00352 3/20 0.41
LMNA P02545 3/20 0.41
ALOX12 P18054 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP1A2 P05177 2/20 0.39
HPGD P15428 1/20 0.39
ADRA2A P08913 2/20 0.39
ADRA2B P18089 2/20 0.39
ADRA2C P18825 2/20 0.39
SLC2A1 P11166 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GAA P10253 1/20 0.38
ATM Q13315 1/20 0.38
KDM4E B2RXH2 1/20 0.37
AGTR1 P30556 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5017354 0.76 IDO1 (0.41) CYP2C9CYP3A4CYP2C19MAPTALDH1A1
SCHEMBL3387040 0.75 MAPT (0.49) CYP2C9CYP2C19MAPTALDH1A1LMNA
SCHEMBL2152203 0.75 GAA (0.51) CYP2C9CYP3A4CYP2C19MAPTALDH1A1
SCHEMBL29739557 0.72 MAPT (0.49) CYP2C9MAPTALDH1A1LMNAALOX12
SCHEMBL10020557 0.72 MAPT (0.49) CYP2C9MAPTALDH1A1LMNAALOX12
SCHEMBL8685241 0.71 ALDH1A1 (0.48) CYP2C9CYP2C19MAPTALDH1A1LMNA
SCHEMBL2152199 0.70 MEN1 (0.49) MAPTALDH1A1LMNAALOX12CYP1A2
SCHEMBL3156019 0.69 MAPT (0.52) CYP2C9CYP2C19MAPTALDH1A1LMNA
SCHEMBL6234527 0.69 NPC1 (0.47) CYP2C9CYP3A4CYP2C19MAPTALDH1A1
SCHEMBL18557885 0.68 ADRA2A (0.44) CYP2C9MAPTALDH1A1LMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1241458-B1 Optical sampling waveform measuring apparatus with high bandwidth ANRITSU CORP (JP) 2005-06-08 EP claimed
EP-1241458-B1 Optical sampling waveform measuring apparatus with high bandwidth ANRITSU CORP (JP) 2005-06-08 EP disclosed
US-6720548-B2 Optical sampling waveform measuring apparatus aiming at achieving wider band ANRITSU CORPORATION (JP) 2004-04-13 US disclosed
US-20020139924-A1 Optical sampling waveform measuring apparatus aiming at achieving wider band ANRITSU CORPORATION (JP) 2002-10-03 US disclosed
EP-1241458-A1 Optical sampling waveform measuring apparatus with high bandwidth ANRITSU CORPORATION (JP) 2002-09-18 EP disclosed