Albiflorin

Albiflorin

SCHEMBL623462

C[C@]12C[C@@H](O)C3C[C@@]1(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C3(COC(=O)c1ccccc1)C(=O)O2

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SYNJ2 O15056 3/20 0.87
SLC22A1 O15245 1/20 0.49
GRK2 P25098 1/20 0.46
MAOB P27338 1/20 0.40
PTPN1 P18031 1/20 0.37
SLC28A3 Q9HAS3 2/20 0.36
EPHX2 P34913 1/20 0.35
LGALS9 O00182 1/20 0.35
LGALS1 P09382 1/20 0.35
LGALS3 P17931 1/20 0.35
LGALS7; LGALS7B P47929 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Albiflorin SCHEMBL21164770 1.00 SYNJ2 (0.87) SYNJ2SLC22A1GRK2MAOBPTPN1
Albiflorin SCHEMBL22648992 1.00 SYNJ2 (0.87) SYNJ2SLC22A1GRK2MAOBPTPN1
Albiflorin SCHEMBL21315817 1.00 SYNJ2 (0.87) SYNJ2SLC22A1GRK2MAOBPTPN1
Albiflorin SCHEMBL15235363 1.00 SYNJ2 (0.87) SYNJ2SLC22A1GRK2MAOBPTPN1
Albiflorin SCHEMBL29500192 1.00 SYNJ2 (0.87) SYNJ2SLC22A1GRK2MAOBPTPN1
Albiflorin SCHEMBL24008597 1.00 SYNJ2 (0.87) SYNJ2SLC22A1GRK2MAOBPTPN1
Albiflorin SCHEMBL21702839 1.00 SYNJ2 (0.87) SYNJ2SLC22A1GRK2MAOBPTPN1
Albiflorin SCHEMBL13387630 0.98 SYNJ2 (0.85) SYNJ2SLC22A1GRK2MAOBPTPN1
SCHEMBL21325290 0.94 SYNJ2 (0.77) SYNJ2SLC22A1GRK2MAOBPTPN1
Paeonivayin SCHEMBL18504853 0.93 SYNJ2 (1.00) SYNJ2SLC22A1GRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1567 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031496-A Use of paeoniflorin for adjuvant treatment of cancer 北京中医药大学 2026-05-15 CN claimed
US-12616709-B2 Pharmaceutical composition for treating sepsis and use thereof TIANJIN CHASE SUN PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US claimed
US-20260021153-A1 TRADITIONAL CHINESE MEDICINE FORMULATION FOR PREVENTING AND TREATING CONSTIPATION-PREDOMINANT IRRITABLE BOWEL SYNDROME (IBS-C) CENTRE FOR CHINESE HERBAL MEDICINE DRUG DEVELOPMENT LTD (CN) 2026-01-22 US claimed
CN-120131683-A Antidepressant composition and preparation method thereof 天津中医药大学 2025-06-13 CN claimed
CN-120114520-A Blood-nourishing, channel-warming and vein-relaxing traditional Chinese medicine composition for treating peripheral neuropathy and preparation method and application thereof 浙江中医药大学附属第二医院(浙江省新华医院) 2025-06-10 CN claimed
US-20250177467-A1 COMPOSITIONS AND METHODS FOR MODULATING NUCLEAR FACTOR OF ACTIVATED T-CELLS (NFAT) ACTIVITY OF T CELLS UNIV YALE (US) 2025-06-05 US claimed
CN-120053522-A Application of traditional Chinese medicine composition in preparation of medicine for relieving oxaliplatin chemotherapy side reaction 江南大学附属医院 2025-05-30 CN claimed
CN-120053521-A White peony root extract and extraction method and application thereof 宁波立华制药有限公司 2025-05-30 CN claimed
CN-120037281-A Use of Chinese medicinal material extract for preparing medicine or non-medicine composition for improving mitochondrial activity 台湾粒线体应用技术股份有限公司 2025-05-27 CN claimed
CN-119970844-A Preparation process of total glucosides of paeony extract, detection method and application thereof 宁波职业技术学院 2025-05-13 CN claimed
CN-1332651-C Wuji dripping pill for treating liver and stomach diseases and its preparing method ZHENGDA LUZHOU MED SCIENCE (CN) 2007-08-22 CN claimed
EP-1776129-A1 THE USE OF PAEONIA AND EXTRACTS THEREOF WITH GROWTH PROMOTING ACTIVITY IN VETERINARY MEDICINE AND ZOOTECHNICS INDENA S.p.A. (IT) 2007-04-25 EP claimed
WO-2007038610-A2 USE OF NATURAL PRODUCTS FOR TREATMENT OF NEUROLOGICAL DISORDERS PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) 2007-04-05 WO claimed
WO-2006012999-A1 THE USE OF PAEONIA AND EXTRACTS THEREOF WITH GROWTH PROMOTING ACTIVITY IN VETERINARY MEDICINE AND ZOOTECHNICS INDENA S.P.A. (IT) 2006-02-09 WO claimed
CN-1682829-A Wuji dripping pill for treating liver and stomach diseases and its preparing method ZHENGDA LUZHOU MED SCIENCE (CN) 2005-10-19 CN claimed
CN-1213762-C Medicine for invigorating kidney, promoting blood circulation and promoting skeleton formation and its prepn XIN YAOLU (CN) 2005-08-10 CN claimed
US-20030232102-A1 Total glycosides of paeony, method to prepare the same and uses thereof ZHAO XINXIAN (CN) 2003-12-18 US claimed
CN-1403113-A Medicine for tonifying kidney, promoting blood circulation and generating bone and preparation method thereof XIN YAOLU (CN) 2003-03-19 CN claimed
WO-2002085395-A1 TOTAL GLYCOSIDES OF PAEONY, METHOD TO PREPARE THE SAME AND USES THEREOF SANJIU MEDICAL & PHARMACEUTICAL CO., LTD. (CN) 2002-10-31 WO claimed
CN-1077386-A A kind of Chinese patent medicine for the treatment of angina pectoris PLA AIRFORCE GENERAL HOSPITAL (CN) 1993-10-20 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021153-A1 TRADITIONAL CHINESE MEDICINE FORMULATION FOR PREVENTING AND TREATING CONSTIPATION-PREDOMINANT IRRITABLE BOWEL SYNDROME (IBS-C) VIP, RDX, SI SYNJ2 1978/4885SLC22A1 2433/4885GRK2 880/4885
US-20030232102-A1 Total glycosides of paeony, method to prepare the same and uses thereof UGT2B7, UGT1A7, CYP3A7 SYNJ2 1443/4885SLC22A1 1039/4885GRK2 2555/4885
US-12616709-B2 Pharmaceutical composition for treating sepsis and use thereof CYP3A43, CYP4A22, SF1 SYNJ2 1279/4885SLC22A1 751/4885GRK2 2551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.