SCHEMBL345074

SCHEMBL345074

C=C(C)C(=O)OCCOP(=O)(O)Oc1ccc(OC)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 2/20 0.42
THRB P10828 1/20 0.40
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TSHR P16473 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
F2RL1 P55085 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6234773 0.92 POLB (0.46) POLBAPEX1HTTTDP1MAPT
SCHEMBL105672 0.88 ALDH1A1 (0.49) POLBAPEX1HTTTDP1THRB
SCHEMBL28104073 0.87 POLB (0.43) POLBAPEX1HTTTDP1MAPT
Phosphoric Acid SCHEMBL17764817 0.86 ALDH1A1 (0.48) POLBAPEX1HTTTDP1THRB
SCHEMBL20283752 0.86 TDP1 (0.43) POLBAPEX1HTTTDP1MAPT
SCHEMBL28231108 0.84 POLB (0.42) POLBAPEX1HTTTDP1MAPT
SCHEMBL17488930 0.82 ALDH1A1 (0.43) POLBAPEX1HTTTDP1THRB
SCHEMBL30049444 0.81 THRB (0.44) TDP1THRBALDH1A1SMN1; SMN2TSHR
SCHEMBL472594 0.81 POLB (0.44) POLBAPEX1HTTTDP1MAPT
SCHEMBL7052527 0.80 POLB (0.50) POLBAPEX1HTTTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12377026-B2 Dental adhesive material kit KURARAY NORITAKE DENTAL INC. (JP) 2025-08-05 US claimed
JP-63225309-A None JP disclosed
JP-63286484-A None JP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
EP-3880156-B1 STORAGE STABLE TWO-COMPONENT DUAL CURE DENTAL COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-08-20 EP disclosed
EP-4175584-B1 PROCESS FOR PRODUCING A SURFACE-MODIFIED DENTAL ARTICLE SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-07-30 EP disclosed
US-20240358603-A1 One-Part Dental Adhesive Composition for Fixing Dental Composite Materials SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-10-31 US disclosed
US-12070514-B2 One-part dental adhesive composition for fixing dental composite materials SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-08-27 US disclosed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
US-11998417-B2 Process for producing a surface-modified dental article SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-06-04 US disclosed
US-20030055123-A1 Dental cement composition KURARAY CO. LTD, (JP) 2003-03-20 US disclosed
CN-1394566-A Tooth cement agent composition KURARAY CO (JP) 2003-02-05 CN disclosed
EP-1269968-A1 Dental cement composition KURARAY CO., LTD. (JP) 2003-01-02 EP disclosed
EP-1269967-A1 Dental composition kit KURARAY CO., LTD. (JP) 2003-01-02 EP disclosed
EP-0572227-B1 Use of an emulsion of a polymer comprising (meth)acrylate units as a dental adhesive MITSUI CHEMICALS INC (JP) 2000-08-23 EP disclosed
US-5629361-A ANTIHYPERSENSITIVE FILMS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-05-13 US disclosed
US-5554669-A DENTAL ADHESIVES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-09-10 US disclosed
EP-0572227-A1 Polymer having (meth)acrylate unit, emulsion thereof, processes for their productions, and adhesive compositions containing the emulsion MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-12-01 EP disclosed
JP-S63286484-A PHOTOCURING ADHESIVE UBE IND LTD 1988-11-24 JP disclosed
JP-S63225309-A DENTAL ETCHING AGENT UBE IND LTD 1988-09-20 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358603-A1 One-Part Dental Adhesive Composition for Fixing Dental Composite Materials CDH1, F12, ACTN1 POLB 279/4885APEX1 85/4885HTT 4115/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 POLB 1067/4885APEX1 65/4885HTT 1934/4885
US-12070514-B2 One-part dental adhesive composition for fixing dental composite materials CDH1, F12, ACTN1 POLB 279/4885APEX1 85/4885HTT 4115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.