Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22119888 | 0.84 | CYP3A4 (0.46) | HSD17B10ALDH1A1CYP3A4TSHRTTR | |
| SCHEMBL272067 | 0.83 | HSD17B10 (0.55) | HSP90AA1HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL580906 | 0.83 | CA1 (0.55) | ALDH1A1CYP3A4TTRCA1CA2 | |
| SCHEMBL11178426 | 0.82 | CYP3A4 (0.52) | ALDH1A1CYP3A4TSHRCA1CA2 | |
| SCHEMBL20717652 | 0.82 | HSD17B10 (0.44) | HSP90AA1HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL3728543 | 0.79 | LMNA (0.36) | HSD17B10ALDH1A1CYP3A4TSHRTTR | |
| SCHEMBL10528411 | 0.76 | HSP90AA1 (0.57) | HSP90AA1HSD17B10ALDH1A1CYP3A4TSHR | |
| SCHEMBL14216960 | 0.76 | CA1 (0.48) | ALDH1A1CYP3A4TTRCA1CA2 | |
| SCHEMBL3788864 | 0.73 | CYP3A4 (0.59) | HSD17B10ALDH1A1CYP3A4TSHRTTR | |
| SCHEMBL8840934 | 0.73 | CA1 (0.50) | ALDH1A1CYP3A4TTRRECQLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1215103-C | Process for the preparation of polycarbonates | DOW GLOBAL TECHNOLOGIES CO (US) | 2005-08-17 | — | — | CN | disclosed |
| EP-1274762-B1 | POLYCARBONATE PREPARATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2005-05-11 | — | — | EP | disclosed |
| CN-1420901-A | Polycarbonate preparation process | DOW GLOBAL TECHNOLOGIES CO (US) | 2003-05-28 | — | — | CN | disclosed |
| US-6225436-B1 | REACTING PHOSGENE AND DIHYDRIC PHENOL; ADDING ACYL HALIDE; ADDING A CHAIN TERMINATOR TO THE REACTION MIXTURE; COMPLETING POLYMERIZATION REACTION | THE DOW CHEMICAL COMPANY | 2001-05-01 | — | — | US | disclosed |
| EP-0941268-A1 | POLYCARBONATES | THE DOW CHEMICAL COMPANY (US) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998022522-A1 | POLYCARBONATES | THE DOW CHEMICAL COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |
| US-RE35499-E | MOLDED ARTICLES SUCH AS COMPACT DISKS | THE DOW CHEMICAL COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0699702-A2 | Reaction products of carbonyl compounds and dihydric phenols | THE DOW CHEMICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5128429-A | Low temperature block polymerization without randomization | RAYCHEM LIMITED (GB) | 1992-07-07 | — | — | US | disclosed |
| EP-0154506-B1 | PREPARATION OF ORGANIC POLYMERS | RAYCHEM LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-4378454-A | DETERMINATION OF END-POINT FOR ADDITION OF PHOSGERNE WITH 4-(P-NITROBENZYL)-PYRIDINE | THE DOW CHEMICAL COMPANY (US) | 1983-03-29 | — | — | US | disclosed |
| US-4210741-A | Phenolphthalein-dihydroxy aromatic compound polycarbonates | THE DOW CHEMICAL COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
| US-4195156-A | ALKALI METAL SALTS OF DIHYDROXY- BENZENE MONO OR DI SULFONIC ACIDS AS COMONOMERS | THE DOW CHEMICAL COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4168368-A | STRESS RESISTANCE | THE DOW CHEMICAL COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4156769-A | Process for making polycarbonates using 1,1-dimethyl urea compounds as the catalysts | THE DOW CHEMICAL COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4100139-A | Polycarbonates incorporating epihalohydrin residues | THE DOW CHEMICAL COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4059566-A | Process for controlling the molecular weight of polycarbonates using ammonia or ammonia compounds | THE DOW CHEMICAL COMPANY (US) | 1977-11-22 | — | — | US | disclosed |
| US-4055544-A | Process for making polycarbonates using ammonia or ammonia compounds as the catalysts | THE DOW CHEMICAL COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4020045-A | METALLIC SULFITES | THE DOW CHEMICAL COMPANY (US) | 1977-04-26 | — | — | US | disclosed |
| US-3992357-A | THERMOPLASTIC | THE DOW CHEMICAL COMPANY (US) | 1976-11-16 | — | — | US | disclosed |