Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.64 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618230 | 0.84 | CYP1A2 (0.53) | SIGMAR1IDO1SMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL27940425 | 0.83 | IDO1 (0.56) | SIGMAR1IDO1PNMTTAAR1NPC1 | |
| SCHEMBL6237103 | 0.82 | IDO1 (0.46) | SIGMAR1IDO1TAAR1ALDH1A1 | |
| SCHEMBL6240433 | 0.80 | CYP3A4 (0.51) | IDO1PNMTTAAR1 | |
| SCHEMBL6235212 | 0.80 | IDO1 (0.45) | SIGMAR1IDO1TAAR1SMN1; SMN2NPC1 | |
| SCHEMBL10458219 | 0.76 | IDO1 (0.55) | SIGMAR1IDO1PNMTTAAR1NPC1 | |
| SCHEMBL7263108 | 0.76 | SIGMAR1 (0.71) | SIGMAR1IDO1PNMTTAAR1CYP2D6 | |
| SCHEMBL6237709 | 0.76 | DRD2 (0.47) | TAAR1NPC1RAB9ACARM1CYP1A2 | |
| SCHEMBL30873130 | 0.75 | IDO1 (0.68) | SIGMAR1IDO1PNMTTAAR1SMN1; SMN2 | |
| SCHEMBL865549 | 0.75 | IDO1 (0.68) | SIGMAR1IDO1PNMTTAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011697-A2 | SULFONAMIDE DERIVATIVES WITH ACTIVITY ON PROTEIN KINASE A AND B | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |