Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PNMT | P11086 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | MC4R | P32245 | 2/20 | 0.56 |
| ▸ | MC5R | P33032 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MARS1 | P56192 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805116 | 0.93 | SIGMAR1 (0.62) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11089154 | 0.88 | CYP1A2 (0.66) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9903437 | 0.85 | SIGMAR1 (0.53) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10098863 | 0.85 | SIGMAR1 (0.53) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8987672 | 0.83 | L3MBTL1 (0.65) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9618249 | 0.83 | CYP1A2 (0.61) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7805399 | 0.81 | POLB (0.55) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14058901 | 0.81 | SMN1; SMN2 (0.59) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL18768914 | 0.81 | CYP1A2 (0.58) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4024603 | 0.81 | CYP1A2 (0.58) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097618-A1 | MORPHOLINYLMETHYLUREAS CCR-3 RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2003-11-27 | — | — | WO | disclosed |
| US-4315846-A | FUNGICIDES | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1982-02-16 | — | — | US | disclosed |
| EP-0037861-A1 | Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1981-10-21 | — | — | EP | disclosed |