Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235445 | 0.92 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6236777 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6236432 | 0.83 | BCHE (0.46) | SMN1; SMN2KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL6233374 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2KMT2AMEN1HTTKDM4E | |
| SCHEMBL6231782 | 0.80 | MAOB (0.43) | SMN1; SMN2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL6233378 | 0.78 | CD274 (0.43) | KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6232919 | 0.77 | PTPRZ1 (0.44) | KMT2AMEN1LMNANPSR1MAOA | |
| SCHEMBL6271865 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AMEN1HTTKDM4E | |
| SCHEMBL6235523 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL6236888 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP3A4CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |