Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232235 | 0.87 | KDM4A (0.43) | ALDH1A1L3MBTL1MAPTKDM4EHSD17B10 | |
| SCHEMBL6989757 | 0.84 | MAPT (0.47) | ALDH1A1L3MBTL1MAPTKDM4EKMT2A | |
| SCHEMBL6989518 | 0.84 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL6988723 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL6985789 | 0.82 | HDAC1 (0.51) | ALDH1A1L3MBTL1MAPTKDM4EHSD17B10 | |
| SCHEMBL6235626 | 0.82 | GPBAR1 (0.47) | ALDH1A1L3MBTL1MAPTKDM4EKMT2A | |
| SCHEMBL5210605 | 0.80 | CFTR (0.55) | ALDH1A1L3MBTL1MAPTKDM4EKMT2A | |
| SCHEMBL6232231 | 0.80 | KDM4A (0.52) | ALDH1A1L3MBTL1MAPTKDM4EALKBH2 | |
| SCHEMBL6992829 | 0.78 | MAPT (0.46) | ALDH1A1L3MBTL1MAPTKDM4EKMT2A | |
| SCHEMBL5808527 | 0.76 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1MAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |