Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | PREP | P48147 | 3/20 | 0.40 |
| ▸ | FAP | Q12884 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CTSE | P14091 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | MC1R | Q01726 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044622 | 0.89 | CTSK (0.38) | CTSKCTSLCTSSCTSBPREP | |
| SCHEMBL6235462 | 0.89 | CCR1 (0.46) | CTSKCTSLCTSSCTSBPREP | |
| SCHEMBL4053232 | 0.88 | CTSK (0.48) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL6211183 | 0.87 | CTSK (0.42) | CTSKCTSLCTSSCTSBPREP | |
| SCHEMBL4041378 | 0.86 | CTSK (0.44) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL4039999 | 0.85 | CTSK (0.54) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL4040706 | 0.85 | CTSK (0.45) | CTSKCTSLCTSSCTSBPREP | |
| SCHEMBL6235917 | 0.85 | CTSK (0.46) | CTSKCTSLCTSSPREPFAP | |
| SCHEMBL4045026 | 0.84 | CTSK (0.36) | CTSKCTSLCTSSCTSBPREP | |
| SCHEMBL6237514 | 0.84 | CTSK (0.46) | CTSKCTSLCTSSCTSBPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |