Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 13/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.49 |
| ▸ | CTSV | O60911 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235743 | 0.87 | PDCD1 (0.39) | PDCD1CD274CTSVCTSLMEN1 | |
| SCHEMBL6233814 | 0.85 | FFAR4 (0.45) | CD274MEN1KMT2A | |
| SCHEMBL6254681 | 0.84 | PDCD1 (0.41) | PDCD1CD274MEN1MAPTKMT2A | |
| SCHEMBL6254676 | 0.84 | PDCD1 (0.41) | PDCD1CD274MEN1MAPTKMT2A | |
| SCHEMBL6233809 | 0.83 | HTR7 (0.41) | MEN1KMT2A | |
| SCHEMBL6231703 | 0.83 | LMNA (0.53) | MEN1MAPTKMT2A | |
| SCHEMBL6231706 | 0.83 | LMNA (0.53) | MEN1MAPTKMT2A | |
| SCHEMBL6233689 | 0.83 | CD274 (0.45) | CD274MEN1KMT2A | |
| SCHEMBL6233811 | 0.83 | HTR7 (0.41) | MEN1KMT2A | |
| SCHEMBL6232051 | 0.82 | MEN1 (0.51) | POLBMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |