Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231703 | 1.00 | LMNA (0.53) | LMNABCHEKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6230153 | 0.91 | MEN1 (0.51) | LMNAKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6232051 | 0.91 | MEN1 (0.51) | LMNAKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6235475 | 0.90 | MTNR1A (0.46) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6276107 | 0.90 | MTNR1A (0.46) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6233814 | 0.89 | FFAR4 (0.45) | LMNABCHEKMT2AMEN1RAB9A | |
| SCHEMBL6235977 | 0.88 | KMT2A (0.57) | LMNABCHEKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6233811 | 0.88 | HTR7 (0.41) | LMNABCHEKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6233809 | 0.88 | HTR7 (0.41) | LMNABCHEKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6233689 | 0.88 | CD274 (0.45) | LMNAKMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |