Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233809 | 0.89 | HTR7 (0.41) | HTR7HTR6SLC2A1CCR5ALDH1A1 | |
| SCHEMBL6233811 | 0.89 | HTR7 (0.41) | HTR7HTR6SLC2A1CCR5ALDH1A1 | |
| SCHEMBL6233689 | 0.89 | CD274 (0.45) | CD274HTR7HTR6SLC2A1CCR5 | |
| SCHEMBL6231703 | 0.89 | LMNA (0.53) | HTR7HTR6ALDH1A1RAB9ALMNA | |
| SCHEMBL6231706 | 0.89 | LMNA (0.53) | HTR7HTR6ALDH1A1RAB9ALMNA | |
| SCHEMBL6232051 | 0.89 | MEN1 (0.51) | HTR7HTR6SLC2A1CCR5ALDH1A1 | |
| SCHEMBL6230153 | 0.89 | MEN1 (0.51) | HTR7HTR6SLC2A1CCR5ALDH1A1 | |
| SCHEMBL6235950 | 0.85 | PDCD1 (0.49) | CD274MEN1KMT2A | |
| SCHEMBL6237847 | 0.84 | BCHE (0.54) | MEN1KMT2ABCHE | |
| SCHEMBL6237852 | 0.84 | BCHE (0.54) | MEN1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |