SCHEMBL623634

SCHEMBL623634

[CH2]COc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.66
LMNA P02545 3/20 0.66
CYP1A2 P05177 2/20 0.66
PGR P06401 2/20 0.66
SLC6A2 P23975 2/20 0.66
CYP2C19 P33261 2/20 0.66
MAPK1 P28482 2/20 0.66
ALDH1A1 P00352 2/20 0.66
CYP2D6 P10635 1/20 0.66
PDE4A P27815 1/20 0.66
HRH1 P35367 1/20 0.66
HTT P42858 1/20 0.66
SLC6A3 Q01959 1/20 0.66
PDE4D Q08499 1/20 0.66
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
USP2 O75604 1/20 0.61
GAA P10253 1/20 0.61
KEAP1 Q14145 1/20 0.61
NFE2L2 Q16236 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29064865 0.88 HPGD (0.62) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL12743862 0.88 LMNA (0.69) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL12415232 0.88 HPGD (0.69) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL29064850 0.87 HPGD (0.61) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL545524 0.86 HPGD (0.68) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL10557539 0.86 HPGD (0.68) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL551152 0.85 HPGD (0.66) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL21880203 0.85 HPGD (0.66) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL808526 0.85 HPGD (0.71) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL5028940 0.85 LMNA (0.66) HPGDLMNACYP1A2PGRSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118308060-A Polyurethane adhesive capable of resisting yellowing and application thereof 广州市奥悦盛体育产业有限公司 2024-07-09 CN claimed
CN-116836145-B Polymerizable photochromic compound and application thereof 重庆蕾明视光科技有限公司 2024-06-14 CN claimed
US-11992825-B2 Adsorption medium, method for production thereof, and use thereof for purification of biomolecules SARTORIUS STEDIM BIOTECH GMBH (DE) 2024-05-28 US claimed
CN-117264113-A Silicone ink-containing intermediate for color contact lens, preparation method thereof and color contact lens 甘肃康视达科技集团有限公司 2023-12-22 CN claimed
CN-116836145-A Polymerizable photochromic compound and application thereof 重庆蕾明视光科技有限公司 2023-10-03 CN claimed
CN-116338831-A Silicon hydrogel and hydrogel combined cornea contact lens and manufacturing method thereof 邓婷 2023-06-27 CN claimed
CN-116265427-A Treatment method of 2- (4-benzoyl-3-hydroxyphenoxy) ethyl 2-acrylate kettle residues 爱生华(苏州)光学有限公司 2023-06-20 CN claimed
CN-115215963-B Blue light resistant cornea contact lens and preparation method thereof 江苏海伦隐形眼镜有限公司 2023-06-13 CN claimed
CN-113912775-B Indicator material and preparation method and application thereof 江苏海伦隐形眼镜有限公司 2023-01-10 CN claimed
CN-113746035-B Method for improving interface voltage resistance of prefabricated cable accessory rubber stress control body 哈尔滨理工大学 2022-12-09 CN claimed
US-9520518-B2 Solar cell module MITSUI CHEMICALS TOHCELLO, INC. (JP) 2016-12-13 US claimed
US-20150144193-A1 SOLAR CELL MODULE MITSUI CHEMICALS TOHCELLO, INC. (JP) 2015-05-28 US claimed
EP-2851964-A1 SOLAR CELL MODULE Mitsui Chemicals Tohcello, Inc. (JP) 2015-03-25 EP claimed
CN-102757527-B anti-UV contact lens formulation LARGAN MEDICAL INC 2015-02-04 CN claimed
CN-102757527-A anti-UV contact lens formulation LARGAN MEDICAL INC 2012-10-31 CN claimed
US-5473001-A Heat and oxidation resistance; photostability ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-12-05 US claimed
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US claimed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US claimed
US-5241067-A Imparting heat, light and oxidation resistance to polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-08-31 US claimed
EP-0303283-A2 2-Hydroxybenzophenone hydrazides and derivatives thereof ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992825-B2 Adsorption medium, method for production thereof, and use thereof for purification of biomolecules NEFM, BPGM, ADM2 HPGD 583/4885LMNA 1049/4885CYP1A2 4207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.