Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 5/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL191774 | 1.00 | KMT2A (0.46) | KMT2AAKR1B10AKR1B1MEN1LMNA | |
| SCHEMBL5481340 | 0.81 | MEN1 (0.52) | KMT2AAKR1B10AKR1B1MEN1LMNA | |
| SCHEMBL5481343 | 0.81 | MEN1 (0.52) | KMT2AAKR1B10AKR1B1MEN1LMNA | |
| SCHEMBL3988188 | 0.79 | G6PD (0.58) | KMT2AAKR1B10AKR1B1MEN1LMNA | |
| SCHEMBL3988193 | 0.79 | G6PD (0.58) | KMT2AAKR1B10AKR1B1MEN1LMNA | |
| SCHEMBL27718581 | 0.77 | MEN1 (0.53) | KMT2AAKR1B10AKR1B1MEN1LMNA | |
| SCHEMBL11350178 | 0.77 | G6PD (0.72) | KMT2AAKR1B10AKR1B1MEN1LMNA | |
| SCHEMBL11226874 | 0.76 | MEN1 (0.48) | KMT2AAKR1B10AKR1B1MEN1LMNA | |
| SCHEMBL11226868 | 0.76 | MEN1 (0.48) | KMT2AAKR1B10AKR1B1MEN1LMNA | |
| SCHEMBL23872369 | 0.76 | GABRA1 (0.69) | KMT2AAKR1B10AKR1B1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1526139-A1 | A process for preparing highly pure androstane 17-beta-carboxylic acids and androstane 17-beta-carbothioic acid fluoromethyl esters | S.N.I.F.F. Italia S.P.A. (IT) | 2005-04-27 | — | — | EP | disclosed |