Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 10/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235327 | 0.85 | ALDH1A1 (0.58) | EPHX2MEN1KMT2AITGB1ITGA5 | |
| SCHEMBL8890210 | 0.81 | EPHX2 (0.48) | EPHX2NR1H4RAB9ALMNAHDAC3 | |
| SCHEMBL13605103 | 0.81 | NR1H4 (0.51) | EPHX2NR1H4RAB9AHDAC3HDAC8 | |
| SCHEMBL7371223 | 0.81 | CTSK (0.49) | EPHX2NR1H4RAB9ALMNAHDAC3 | |
| SCHEMBL29176921 | 0.81 | EPHX2 (0.49) | EPHX2NR1H4RAB9ALMNAHDAC3 | |
| SCHEMBL8890216 | 0.81 | EPHX2 (0.48) | EPHX2NR1H4RAB9ALMNAHDAC3 | |
| SCHEMBL7371090 | 0.81 | CTSK (0.49) | EPHX2NR1H4RAB9ALMNAHDAC3 | |
| SCHEMBL6238643 | 0.81 | SMN1; SMN2 (0.53) | RAB9ALMNAMEN1KMT2AITGB1 | |
| SCHEMBL3556483 | 0.80 | SIGMAR1 (0.55) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL497818 | 0.80 | SIGMAR1 (0.55) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311259-B1 | PHARMACEUTICAL COMPOSITION COMPRISING AN ESTER OF 5-AMINOLEVULINIC ACID AS PHOTOCHEMOTHERAPEUTIC AGENT AND A MUCOADHESIVE AGENT | PHOTOCURE ASA (NO) | 2005-06-15 | — | — | EP | claimed |