Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512172 | 0.86 | HTR6 (0.62) | METHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL13323640 | 0.80 | HDAC3 (0.55) | METHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL6236314 | 0.80 | HTR6 (0.52) | METHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL1971506 | 0.80 | MET (0.66) | METHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL6632663 | 0.80 | HTR6 (0.56) | METHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL29425682 | 0.79 | HDAC1 (0.52) | METHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL28692303 | 0.79 | HDAC1 (0.52) | METHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL18649849 | 0.76 | HDAC3 (0.51) | METHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL20742991 | 0.76 | HTR6 (0.62) | METHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL426117 | 0.74 | HTR6 (0.68) | HDAC3HDAC1HDAC2HDAC10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |