Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 1.00 |
| ▸ | CTSS | P25774 | 10/20 | 1.00 |
| ▸ | CTSL | P07711 | 8/20 | 1.00 |
| ▸ | CTSB | P07858 | 8/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | CTSH | P09668 | 1/20 | 0.45 |
| ▸ | CASP14 | P31944 | 1/20 | 0.45 |
| ▸ | CASP4 | P49662 | 1/20 | 0.45 |
| ▸ | CASP5 | P51878 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259447 | 0.89 | CTSS (0.81) | CTSKCTSSCTSLCTSBHTT | |
| SCHEMBL6235821 | 0.89 | CTSS (0.81) | CTSKCTSSCTSLCTSBHTT | |
| SCHEMBL6238843 | 0.88 | CTSK (0.78) | CTSKCTSSCTSLCTSBROCK1 | |
| SCHEMBL6241051 | 0.87 | CTSS (0.76) | CTSKCTSSCTSLCTSBHTT | |
| SCHEMBL6239841 | 0.85 | CTSS (0.74) | CTSKCTSSCTSLCTSBHTT | |
| SCHEMBL6237549 | 0.85 | CTSS (0.73) | CTSKCTSSCTSLCTSBHTT | |
| SCHEMBL6239326 | 0.85 | CTSK (0.73) | CTSKCTSSCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6237865 | 0.83 | CTSK (0.71) | CTSKCTSSCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6239271 | 0.81 | CTSS (0.69) | CTSKCTSSCTSLCTSBHTT | |
| SCHEMBL6235257 | 0.81 | CTSS (0.68) | CTSKCTSSCTSLCTSBROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | claimed |
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |