Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.73 |
| ▸ | CTSK | P43235 | 4/20 | 0.73 |
| ▸ | CTSL | P07711 | 3/20 | 0.73 |
| ▸ | CTSB | P07858 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259447 | 0.89 | CTSS (0.81) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL6235821 | 0.89 | CTSS (0.81) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL6241051 | 0.87 | CTSS (0.76) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL6239271 | 0.86 | CTSS (0.69) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL6239841 | 0.85 | CTSS (0.74) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL6239326 | 0.85 | CTSK (0.73) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6236491 | 0.85 | CTSK (1.00) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL6237865 | 0.83 | CTSK (0.71) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6236127 | 0.80 | CTSL (0.60) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL6241632 | 0.79 | CTSS (0.68) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |