Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.69 |
| ▸ | CTSK | P43235 | 6/20 | 0.69 |
| ▸ | CTSL | P07711 | 3/20 | 0.69 |
| ▸ | CTSB | P07858 | 2/20 | 0.69 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | CTSH | P09668 | 1/20 | 0.43 |
| ▸ | CASP14 | P31944 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237549 | 0.86 | CTSS (0.73) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6259447 | 0.86 | CTSS (0.81) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6235821 | 0.86 | CTSS (0.81) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6241051 | 0.83 | CTSS (0.76) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6239841 | 0.82 | CTSS (0.74) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6239326 | 0.81 | CTSK (0.73) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6236491 | 0.81 | CTSK (1.00) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6237865 | 0.80 | CTSK (0.71) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6236127 | 0.77 | CTSL (0.60) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL6241632 | 0.76 | CTSS (0.68) | CTSSCTSKCTSLCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |