Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29276396 | 0.82 | PRKCA (0.44) | TSHRTDP1L3MBTL1ALDH1A1PRKCA | |
| SCHEMBL9742565 | 0.82 | TSHR (0.41) | TSHRTDP1L3MBTL1ALDH1A1PRKCA | |
| SCHEMBL6240956 | 0.80 | TSHR (0.39) | TSHRTDP1L3MBTL1ALDH1A1PRKCA | |
| SCHEMBL6233376 | 0.80 | TSHR (0.39) | TSHRTDP1L3MBTL1ALDH1A1PRKCA | |
| SCHEMBL214007 | 0.79 | MGAM (0.46) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL96009 | 0.79 | MGAM (0.46) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL96394 | 0.79 | MGAM (0.46) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL18087555 | 0.79 | TSHR (0.45) | TSHRTDP1L3MBTL1ALDH1A1PRKCA | |
| SCHEMBL1456508 | 0.79 | TSHR (0.45) | TSHRTDP1L3MBTL1ALDH1A1PRKCA | |
| SCHEMBL7412928 | 0.78 | MAPT (0.41) | TSHRTDP1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005375-A1 | METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS | LANXESS DEUTSCHLAND GMBH (DE) | 2005-01-20 | — | — | WO | disclosed |