Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96394 | 1.00 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL214007 | 1.00 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL14297015 | 0.90 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2224711 | 0.90 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2364323 | 0.88 | GAA (0.45) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1258369 | 0.86 | GAA (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL14297014 | 0.84 | GAA (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6155100 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL10779003 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL3853840 | 0.82 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260085334-A1 | ENGINEERED KETOREDUCTASES FOR THE PREPARATION OF CHIRAL ALCOHOLS AND METHODS THEREOF | ENZYMASTER (NINGBO) BIO-ENGINEERING CO., LTD. (CN) | 2026-03-26 | — | — | US | claimed |
| CN-116199591-B | Industrial preparation method of levocarnitine | 山东齐都药业有限公司 | 2025-06-03 | — | — | CN | claimed |
| EP-4551693-A1 | ENGINEERED KETOREDUCTASES FOR THE PREPARATION OF CHIRAL ALCOHOLS AND METHODS THEREOF | Enzymaster (Ningbo) Bio-Engineering Co., Ltd. (CN) | 2025-05-14 | — | — | EP | claimed |
| CN-119432788-A | Alcohol dehydrogenase mutant with improved (R) -4-chloro-3-hydroxybutyrate production capacity and application thereof | 河南大学 | 2025-02-14 | — | — | CN | claimed |
| CN-118834128-A | Continuous flow synthesis and post-treatment method and device for (R) -3-hydroxy-4-chlorobutyric acid ethyl ester | 浙江工业大学 | 2024-10-25 | — | — | CN | claimed |
| CN-118703459-A | Carbonyl reductase mutant and application thereof | 默沃智造(上海)生物技术有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-117947112-A | Preparation method of (R) -4-chloro-3-hydroxy-ethyl butyrate | 万华化学集团股份有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117757826-A | Recombinant expression plasmid of short-chain dehydrogenase, recombinant genetically engineered bacterium and application thereof | 浙江工业大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117757690-A | Burkholderia cepacia (Burkholderia cepacia) WZ-5 and application thereof | 浙江工业大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117721088-A | Glucose dehydrogenase mutant and use thereof | 万华化学集团股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-110938620-A | Magnetic immobilized yeast cell and application thereof in synthesis of (R) -4-chloro-3-hydroxybutanoate ethyl ester | 浙江工业大学 | 2020-03-31 | — | — | CN | claimed |
| CN-109943482-A | A method of extraction preparation r-4- chloro-3-hydroxyl ethyl butyrate is coupled using enzyme mebrane reactor | 泰州市惠利生物科技有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-104030934-B | A kind of preparation method of levocarnitine compound | 东北制药集团股份有限公司 | 2016-06-15 | — | — | CN | claimed |
| CN-103320403-B | Ketoreductase LEK mutant and application | HANGZHOU NORMAL UNIVERSITY (CN) | 2016-02-10 | — | — | CN | claimed |
| EP-2569275-B1 | A PROCESS FOR THE HYDROGENATION OF KETOESTERS | LONZA AG (CH) | 2016-01-27 | — | — | EP | claimed |
| CN-102844293-B | The method for hydrogenation of ketone ester | LONZA LTD. (CH) | 2016-01-27 | — | — | CN | claimed |
| CN-103289970-B | Ketone reductase LEK, encoding gene, mutant and application of mutant | UNIV HANGZHOU NORMAL | 2015-05-27 | — | — | CN | claimed |
| CN-103923889-A | Hyacinthin reductase mutant | UNIV CHINA PHARMA | 2014-07-16 | — | — | CN | claimed |
| US-8431741-B2 | Process for the hydrogenation of ketoesters | LONZA LTD (CH) | 2013-04-30 | — | — | US | claimed |
| EP-0288994-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS | Chisso Corporation (JP) | 1992-07-22 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085334-A1 | ENGINEERED KETOREDUCTASES FOR THE PREPARATION OF CHIRAL ALCOHOLS AND METHODS THEREOF | ADH1A, CYP4F11, ADH1C | MGAM 618/4885GAA 2068/4885SI 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.