Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96394 | 1.00 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL96009 | 1.00 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL14297015 | 0.90 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2224711 | 0.90 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL2364323 | 0.88 | GAA (0.45) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1258369 | 0.86 | GAA (0.55) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL14297014 | 0.84 | GAA (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6155100 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL10779003 | 0.83 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL3853840 | 0.82 | MGAM (0.50) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 696 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112143688-B | Construction and application of recombinant escherichia coli | 鲁南制药集团股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117947112-A | Preparation method of (R) -4-chloro-3-hydroxy-ethyl butyrate | 万华化学集团股份有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117757826-A | Recombinant expression plasmid of short-chain dehydrogenase, recombinant genetically engineered bacterium and application thereof | 浙江工业大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117721088-A | Glucose dehydrogenase mutant and use thereof | 万华化学集团股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-113652408-B | Carbonyl reductase mutant and application thereof in synthesis of (R) -4-chloro-3-hydroxybutyrate ethyl ester | 华东理工大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117511893-A | Carbonyl reductase mutant and application thereof | 安徽丰原发酵技术工程研究有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117402843-A | Ketoreductase from schizosaccharomyces japonica yFS275 and application thereof | 万华化学集团股份有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-117402839-A | Ketoreductase and application thereof in preparation of (R) -4-chloro-3-hydroxybutyrate | 万华化学集团股份有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-117384868-A | Engineered ketoreductase and method for preparing chiral alcohol compounds | 宁波酶赛生物工程有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-114380706-B | Method and device for continuously preparing L-carnitine at low cost | 浙江财和生物科技有限公司 | 2024-01-09 | — | — | CN | claimed |
| EP-1981831-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | Vaidya, Niteen A. (US) | 2008-10-22 | — | — | EP | claimed |
| WO-2007092264-A2 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2007-08-16 | — | — | WO | claimed |
| US-20070185346-A1 | Kit for automated resolving agent selection and method thereof | VAIDYA NITEEN A | 2007-08-09 | — | — | US | claimed |
| US-7202069-B2 | (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-10 | — | — | US | claimed |
| WO-2005005375-A1 | METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS | LANXESS DEUTSCHLAND GMBH (DE) | 2005-01-20 | — | — | WO | claimed |
| US-20040126857-A1 | (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes | DAICEL CHEMICAL INDUSTRIES, LTD., A JAPAN CORPORATION | 2004-07-01 | — | — | US | claimed |
| US-20020192783-A1 | (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-12-19 | — | — | US | claimed |
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | claimed |
| EP-1179595-A1 | (R)-2-OCTANOL DEHYDROGENASE, PROCESS FOR PRODUCING THE ENZYME, DNA ENCODING THE ENZYME AND PROCESS FOR PRODUCING ALCOHOL BY USING THE SAME | Daicel Chemical Industries, Ltd. (JP) | 2002-02-13 | — | — | EP | claimed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040126857-A1 | (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes | OGA, HOGA1, ADH1A | MGAM 164/4885GAA 938/4885SI 710/4885 |
| US-20020192783-A1 | (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes | OGA, HOGA1, ADH1A | MGAM 164/4885GAA 938/4885SI 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.