Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17950452 | 0.79 | SLC9A1 (0.43) | ERCC5FEN1PARP1LMNATDP1 | |
| SCHEMBL10600690 | 0.79 | POLB (0.43) | POLBMAPK1ATMNPC1CASP3 | |
| SCHEMBL3282387 | 0.74 | KDM4E (0.49) | POLBMAPK1ATMLMNATDP1 | |
| SCHEMBL29016438 | 0.72 | GPR139 (0.46) | ERCC5FEN1POLBPARP1LMNA | |
| SCHEMBL17950672 | 0.71 | KMT2A (0.43) | LMNATDP1KMT2AMEN1 | |
| SCHEMBL10988950 | 0.71 | LMNA (0.43) | POLBLMNATDP1MGAMAMY1A | |
| SCHEMBL29350840 | 0.71 | MEN1 (0.57) | POLBMAPK1ATMLMNATDP1 | |
| SCHEMBL2954 | 0.71 | MEN1 (0.57) | POLBMAPK1ATMLMNATDP1 | |
| SCHEMBL4884291 | 0.69 | MEN1 (0.56) | POLBMAPK1ATMLMNATDP1 | |
| SCHEMBL30546913 | 0.67 | POLB (0.44) | FEN1POLBMAPK1ATMPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007634-A1 | 3-HYDROXY-4-OXO-1,2,3-TRIAZINES AND DERIVATIVES THEREOF FOR AMIDE AND ESTER BOND FORMATION | FRUTAROM LTD. (IL) | 2005-01-27 | — | — | WO | disclosed |