Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034681 | 0.78 | SIGMAR1 (1.00) | SIGMAR1USP2ALDH1A1MAPK1GFER | |
| SCHEMBL1674212 | 0.77 | SIGMAR1 (0.74) | SIGMAR1USP2ALDH1A1MAPK1GFER | |
| SCHEMBL3324949 | 0.77 | SIGMAR1 (0.74) | SIGMAR1USP2ALDH1A1MAPK1GFER | |
| SCHEMBL9510691 | 0.77 | SIGMAR1 (1.00) | SIGMAR1USP2ALDH1A1MAPK1GFER | |
| SCHEMBL3712996 | 0.76 | SIGMAR1 (0.73) | SIGMAR1USP2ALDH1A1MAPK1GFER | |
| SCHEMBL6337882 | 0.76 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL4616164 | 0.76 | SFRP1 (0.54) | SIGMAR1ALDH1A1MAPK1GFERSMN1; SMN2 | |
| SCHEMBL14046920 | 0.74 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL1148907 | 0.74 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2KMT2AMEN1PKM | |
| SCHEMBL3974097 | 0.74 | SIGMAR1 (0.69) | SIGMAR1USP2ALDH1A1MAPK1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |