Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | PRKACG | P22612 | 1/20 | 0.40 |
| ▸ | PRKACB | P22694 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237705 | 0.85 | RAB9A (0.45) | CA1CA2CA9CYP2C19AGXT | |
| SCHEMBL6239312 | 0.84 | SMN1; SMN2 (0.52) | LMNACYP2C9CYP2C19RAB9ASPHK2 | |
| SCHEMBL6235212 | 0.84 | IDO1 (0.45) | IDO1RAB9ANPC1 | |
| SCHEMBL6240427 | 0.83 | CYP3A4 (0.46) | IDO1AGXTSPHK2SPHK1 | |
| SCHEMBL8802965 | 0.79 | CYP2C9 (0.49) | LMNACA1CA2CA9CYP2C9 | |
| SCHEMBL4452224 | 0.79 | IDO1 (0.54) | LMNACA1CA2CA9CYP2C9 | |
| SCHEMBL5003976 | 0.78 | TAAR1 (0.56) | NPC1 | |
| SCHEMBL6237103 | 0.78 | IDO1 (0.46) | LMNAIDO1AGXTPRKACAPRKACG | |
| Trifluoroacetic Acid SCHEMBL7760506 | 0.77 | SMN1; SMN2 (0.46) | LMNASPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL5004496 | 0.77 | TAAR1 (0.55) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011697-A2 | SULFONAMIDE DERIVATIVES WITH ACTIVITY ON PROTEIN KINASE A AND B | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | claimed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| WO-2005011697-A2 | SULFONAMIDE DERIVATIVES WITH ACTIVITY ON PROTEIN KINASE A AND B | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |