Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891457 | 0.81 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ALOX15GAAMAPT | |
| SCHEMBL6382888 | 0.81 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTCYP2D6SLC1A3 | |
| SCHEMBL10485701 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ALOX15GAAMAPT | |
| SCHEMBL15087211 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CYP3A4ALOX15GAAMAPT | |
| SCHEMBL8440516 | 0.76 | — | — | |
| SCHEMBL1387211 | 0.75 | — | — | |
| SCHEMBL11749020 | 0.74 | ALDH1A1 (0.57) | ALDH1A1CYP3A4ALOX15GAAMAPT | |
| SCHEMBL23902901 | 0.74 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTCYP2D6SLC1A3 | |
| SCHEMBL15064216 | 0.74 | — | — | |
| SCHEMBL1152092 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022093792-A1 | ELECTROLYTE ADDITIVES CONTAINING ONE, TWO, OR MORE TRIPLE-BONDED MOIETIES FOR SILICON ANODE-BASED BATTERIES | ENEVATE CORPORATION (US) | 2022-05-05 | — | — | WO | claimed |
| WO-2024180230-A1 | 5-METHYL-1,3-DIHYDROISOBENZOFURAN-4-OL PREPARED FROM 5-METHYLFURFURYL ALCOHOL AND PROPARGYL ALCOHOL | DSM IP ASSETS B.V. (NL) | 2024-09-06 | — | — | WO | disclosed |
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-21 | — | — | US | disclosed |
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2023-02-21 | — | — | US | disclosed |
| US-11539077-B2 | Electrolyte additives containing one, two, or more triple-bonded moieties for silicon anode-based li-ion batteries | ENEVATE CORPORATION (US) | 2022-12-27 | — | — | US | disclosed |
| WO-2022093792-A1 | ELECTROLYTE ADDITIVES CONTAINING ONE, TWO, OR MORE TRIPLE-BONDED MOIETIES FOR SILICON ANODE-BASED BATTERIES | ENEVATE CORPORATION (US) | 2022-05-05 | — | — | WO | disclosed |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | US | disclosed |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | US | disclosed |
| US-11197859-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2021-12-14 | — | — | US | disclosed |
| US-11197859-B2 | Hydantoin derivatives useful as Kv3 inhibitors | AUTIFONY THERAPEUTICS LIMITED (GB) | 2021-12-14 | — | — | US | disclosed |
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |
| US-20100143980-A1 | SYNTHESIS OF NOVEL XYLOSIDES AND POTENTIAL USES THEREOF | BALAGURUNATHAN KUBERAN | 2010-06-10 | — | — | US | disclosed |
| US-20100143980-A1 | SYNTHESIS OF NOVEL XYLOSIDES AND POTENTIAL USES THEREOF | BALAGURUNATHAN KUBERAN | 2010-06-10 | — | — | US | disclosed |
| US-20050258553-A1 | Method for the organometallic production of organic intermediate products comprising carbon-heteroatom bonds achieved by the deprotonation of heteroatoms | ARCHIMICA GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
| EP-1537125-A1 | METHOD FOR THE ORGANOMETALLIC PRODUCTION OF ORGANIC INTERMEDIATE PRODUCTS COMPRISING CARBON-HETEROATOM BONDS ACHIEVED BY THE DEPROTONATION OF HETEROATOMS | Clariant GmbH (DE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004024737-A1 | METHOD FOR THE ORGANOMETALLIC PRODUCTION OF ORGANIC INTERMEDIATE PRODUCTS COMPRISING CARBON-HETEROATOM BONDS ACHIEVED BY THE DEPROTONATION OF HETEROATOMS | CLARIANT GMBH (DE) | 2004-03-25 | — | — | WO | disclosed |
| JP-2002105069-A | METHOD FOR PRODUCING PROPARGYLFURFURYL ALCOHOLS | SUMITOMO CHEM CO LTD | 2002-04-10 | — | — | JP | disclosed |
| CN-1104849-A | Fuming, hot-vaporizing insecticide for killing flies, and method for killing flies with the same | DAINPPON JOCHUGIKU CO LTD (JP) | 1995-07-12 | — | — | CN | disclosed |
| US-4496767-A | REARRANGEMENT, ESTERIFICATION AND REDUCTION OF A FURAN-CARBINOL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11583527-B2 | Hydantoin derivatives useful as Kv3 inhibitors | KCNN3, KCND3, KCNA3 | ALDH1A1 1966/4885CYP3A4 943/4885ALOX15 4158/4885 |
| US-20220054490-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | KCNN3, KCND3, KCNA3 | ALDH1A1 1966/4885CYP3A4 943/4885ALOX15 4158/4885 |
| US-20050258553-A1 | Method for the organometallic production of organic intermediate products comprising carbon-heteroatom bonds achieved by the deprotonation of heteroatoms | IGLV6-57, ICMT, INTS6 | ALDH1A1 883/4885CYP3A4 94/4885ALOX15 1624/4885 |
| US-20100143980-A1 | SYNTHESIS OF NOVEL XYLOSIDES AND POTENTIAL USES THEREOF | CSGALNACT1, ST3GAL3, FUT6 | ALDH1A1 936/4885CYP3A4 1078/4885ALOX15 856/4885 |
| US-11539077-B2 | Electrolyte additives containing one, two, or more triple-bonded moieties for silicon anode-based li-ion batteries | SELENOI, SIK1, SIK2 | ALDH1A1 264/4885CYP3A4 4627/4885ALOX15 4535/4885 |
| US-11197859-B2 | Hydantoin derivatives useful as Kv3 inhibitors | KCNN3, KCND3, KCNA3 | ALDH1A1 1966/4885CYP3A4 943/4885ALOX15 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.