Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153825 | 0.86 | LMNA (0.45) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL6154465 | 0.82 | MMP1 (0.32) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL5814007 | 0.80 | LMNA (0.45) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL28617289 | 0.78 | LMNA (0.39) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL5174591 | 0.78 | LMNA (0.39) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL3681340 | 0.78 | LMNA (0.39) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL29983795 | 0.78 | GABRR1 (0.48) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL27525813 | 0.78 | LMNA (0.39) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL12219258 | 0.78 | GABRR1 (0.48) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL3681337 | 0.78 | LMNA (0.39) | LMNATSHRMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005375-A1 | METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS | LANXESS DEUTSCHLAND GMBH (DE) | 2005-01-20 | — | — | WO | claimed |
| WO-2005005375-A1 | METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS | LANXESS DEUTSCHLAND GMBH (DE) | 2005-01-20 | — | — | WO | disclosed |