Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153825 | 0.86 | LMNA (0.45) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL6155095 | 0.82 | FAAH (0.36) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL27901353 | 0.80 | LMNA (0.41) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL5814007 | 0.80 | LMNA (0.45) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL3681340 | 0.78 | LMNA (0.39) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL6237469 | 0.78 | LMNA (0.39) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL12219258 | 0.78 | GABRR1 (0.48) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL29983795 | 0.78 | GABRR1 (0.48) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL28617289 | 0.78 | LMNA (0.39) | LMNATSHRMMP1MMP2MMP3 | |
| SCHEMBL27525813 | 0.78 | LMNA (0.39) | LMNATSHRMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005375-A1 | METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS | LANXESS DEUTSCHLAND GMBH (DE) | 2005-01-20 | — | — | WO | claimed |
| EP-1213354-B1 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL CO (JP) | 2007-05-30 | — | — | EP | disclosed |
| US-6884607-B2 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-26 | — | — | US | disclosed |
| US-20050019816-A1 | Process for producing optically active-4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-01-27 | — | — | US | disclosed |
| US-20030134402-A1 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-0829472-B1 | IMPROVED PROCESS FOR PRODUCING 4-HYDROXY-2-PYRROLIDONE | DAISO CO LTD (JP) | 2002-08-21 | — | — | EP | disclosed |
| EP-1213354-A2 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-5869694-A | Process for preparing 4-hydroxy-2-pyrrolidone | DAISO CO., LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0829472-A1 | IMPROVED PROCESS FOR PRODUCING 4-HYDROXY-2-PYRROLIDONE | DAISO CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134402-A1 | Process for producing optically active 4-halo-3-hydroxybutanoate | RNGTT, HMBS, POLB | LMNA 2312/4885TSHR 3106/4885MMP1 3345/4885 |
| US-20050019816-A1 | Process for producing optically active-4-halo-3-hydroxybutanoate | RNGTT, POLB, POLL | LMNA 2401/4885TSHR 2889/4885MMP1 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.