SCHEMBL6154465

SCHEMBL6154465

CCC(C)OC(=O)CC(O)CI

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP9 P14780 1/20 0.32
MMP13 P45452 1/20 0.32
EPHX2 P34913 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
MAPT P10636 1/20 0.30
SLC22A6 Q4U2R8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6153342 0.90 MMP1 (0.38) MMP1MMP2MMP3MMP9MMP13
SCHEMBL9745593 0.86 MMP1 (0.35) MMP1MMP2MMP3MMP9MMP13
SCHEMBL15478217 0.82 LMNA (0.36) MMP1MMP2MMP3MMP9MMP13
SCHEMBL4025536 0.82 SLC22A6 (0.52) MMP1MMP2MMP3MMP9MMP13
SCHEMBL19821829 0.82 TSHR (0.36) MMP1MMP2MMP3MMP9MMP13
SCHEMBL6237469 0.82 LMNA (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL23072789 0.81 GABRR1 (0.43) MMP1MMP2MMP3MMP9MMP13
SCHEMBL26363332 0.81 LMNA (0.33) MMP1MMP2MMP3MMP9MMP13
SCHEMBL6155095 0.81 FAAH (0.36) MMP1MMP2MMP3MMP9MMP13
SCHEMBL6157234 0.81 FAAH (0.36) MMP1MMP2MMP3MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005005375-A1 METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS LANXESS DEUTSCHLAND GMBH (DE) 2005-01-20 WO claimed
EP-0970947-B1 PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES KANEKA CORP (JP) 2005-01-26 EP disclosed
WO-2005005375-A1 METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS LANXESS DEUTSCHLAND GMBH (DE) 2005-01-20 WO disclosed
US-6140527-A Process for producing butyric ester derivatives KANEKA CORPORATION (JP) 2000-10-31 US disclosed
EP-0970947-A1 PROCESS FOR PRODUCING BUTYRIC ESTER DERIVATIVES KANEKA CORPORATION (JP) 2000-01-12 EP disclosed