Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385367 | 0.81 | CYP1A2 (0.44) | ACHEPTGS2CALM1 | |
| SCHEMBL5403026 | 0.78 | TYR (0.54) | TDP1CYP3A4HPGDBCHETYR | |
| SCHEMBL4646583 | 0.73 | TDP1 (0.75) | TDP1CYP3A4HPGDPTPN1TYR | |
| SCHEMBL5384722 | 0.73 | KDM4E (0.41) | TDP1CYP3A4HPGDCYP2C19BCHE | |
| SCHEMBL5384344 | 0.72 | BCHE (0.35) | TDP1BCHETYRACHEABL1 | |
| SCHEMBL11882610 | 0.72 | TDP1 (0.60) | TDP1CYP3A4HPGDABL1ABCB1 | |
| SCHEMBL5710919 | 0.69 | ALDH1A1 (0.45) | TDP1CYP3A4HPGDMAPK1MAPT | |
| SCHEMBL5393452 | 0.69 | HMGCR (0.41) | CYP3A4BCHETYRACHE | |
| SCHEMBL5390114 | 0.69 | ADRA1A (0.56) | CYP2C19ACHEMAPK1MAPT | |
| SCHEMBL5378291 | 0.69 | LTA4H (0.47) | TDP1BCHETYRACHEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534227-A1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004022016-A1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-03-18 | — | — | WO | disclosed |