Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403026 | 0.88 | TYR (0.54) | MAPTALDH1A1BCHETYRACHE | |
| SCHEMBL5710919 | 0.86 | ALDH1A1 (0.45) | LTA4HMAPTALDH1A1HSD17B10NQO1 | |
| SCHEMBL5377925 | 0.85 | TYR (0.44) | TYR | |
| SCHEMBL7148830 | 0.77 | ADRA2A (0.46) | LTA4HMAPTALDH1A1HSD17B10NQO1 | |
| SCHEMBL339500 | 0.77 | LTA4H (0.57) | LTA4HMAPTALDH1A1HSD17B10NQO1 | |
| SCHEMBL1051397 | 0.77 | LTA4H (0.57) | LTA4HMAPTALDH1A1HSD17B10NQO1 | |
| SCHEMBL5389460 | 0.76 | PTGS1 (0.38) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5380194 | 0.75 | LTA4H (0.39) | LTA4HMAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL5393005 | 0.75 | BCHE (0.33) | MAPTALDH1A1HSD17B10BCHEACHE | |
| SCHEMBL5377820 | 0.75 | ALDH1A1 (0.42) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300472-B2 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-01-04 | — | — | US | disclosed |
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | disclosed |
| EP-1715839-A1 | AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-11-02 | — | — | EP | disclosed |
| US-7105032-B2 | Agents used for dyeing keratinous fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-09-12 | — | — | US | disclosed |
| WO-2005063178-A1 | AGENTS FOR COLOURING FIBRES CONTAINING KERATIN, COMPRISING HETEROCYCLIC ENAMINES AND REACTIVE CARBONYL COMPOUNDS AND/OR REACTION PRODUCTS THEREOF | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-07-14 | — | — | WO | disclosed |
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | HENKEL AG & CO. KGAA (DE) | 2005-07-07 | — | — | US | disclosed |
| EP-1534227-A1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004022016-A1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | KRT18, TUBB3, DSG1 | LTA4H 3227/4885MAPT 259/4885ALDH1A1 343/4885 |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | KRT18, COL1A1, CYC1 | LTA4H 3727/4885MAPT 2036/4885ALDH1A1 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.