Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3804979 | 0.82 | MAOB (0.61) | MAOBSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL6237903 | 0.80 | RAB9A (0.55) | MAOBSMN1; SMN2MRGPRX4TP53PKM | |
| SCHEMBL22619020 | 0.79 | ACHE (0.61) | SMN1; SMN2RAB9ANPC1LMNAELANE | |
| SCHEMBL6243823 | 0.77 | FFAR1 (0.53) | MRGPRX4PTPRCPTPN1NR4A2 | |
| SCHEMBL3916599 | 0.75 | APP (0.63) | MAOBMAOALMNAHIF1AIDO1 | |
| SCHEMBL30674750 | 0.75 | APP (0.63) | MAOBMAOALMNAHIF1AIDO1 | |
| SCHEMBL4246892 | 0.75 | KMT2A (0.63) | SMN1; SMN2TP53NFKB1NFKB2RELA | |
| SCHEMBL9060683 | 0.74 | APP (0.64) | MAOBMAOAIDO1NR4A2 | |
| SCHEMBL5708187 | 0.74 | APP (0.61) | MAOBMAOALMNAHIF1AIDO1 | |
| SCHEMBL16415825 | 0.74 | PPARA (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |