Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 15/20 | 0.52 |
| ▸ | MMP13 | P45452 | 6/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240212 | 0.90 | MMP1 (0.51) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL6241133 | 0.89 | MMP1 (0.54) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL6238179 | 0.89 | MMP1 (0.54) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL6238727 | 0.89 | MMP1 (0.54) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL6238194 | 0.87 | MMP1 (0.55) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL6233856 | 0.87 | ADAM17 (0.43) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL6239672 | 0.86 | ADAM17 (0.44) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL6234233 | 0.85 | ADAM17 (0.58) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL6241443 | 0.85 | ADAM17 (0.56) | MMP1ADAM17MMP13 | |
| SCHEMBL6240990 | 0.85 | MMP1 (0.57) | MMP1ADAM17MMP13MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104412-B1 | TACE INHIBITORS | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | claimed |