Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 11/20 | 0.54 |
| ▸ | MMP13 | P45452 | 3/20 | 0.54 |
| ▸ | MMP8 | P22894 | 4/20 | 0.51 |
| ▸ | MMP3 | P08254 | 4/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238179 | 1.00 | MMP1 (0.54) | MMP1ADAM17MMP13MMP8MMP3 | |
| SCHEMBL6241133 | 1.00 | MMP1 (0.54) | MMP1ADAM17MMP13MMP8MMP3 | |
| SCHEMBL6238194 | 0.92 | MMP1 (0.55) | MMP1ADAM17MMP13MMP8MMP3 | |
| SCHEMBL6240359 | 0.91 | MMP1 (0.53) | MMP1ADAM17MMP13MMP8MMP3 | |
| SCHEMBL6238983 | 0.91 | MMP1 (0.53) | MMP1ADAM17MMP13MMP8MMP3 | |
| SCHEMBL6237935 | 0.89 | MMP1 (0.52) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL6235547 | 0.89 | MMP1 (0.51) | MMP1ADAM17MMP13MMP8MMP3 | |
| SCHEMBL6242757 | 0.87 | MMP1 (0.59) | MMP1ADAM17MMP13 | |
| SCHEMBL6233856 | 0.87 | ADAM17 (0.43) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL6239622 | 0.85 | MMP1 (0.65) | MMP1ADAM17MMP13MMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104412-B1 | TACE INHIBITORS | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | claimed |