Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.68 |
| ▸ | CTSK | P43235 | 10/20 | 0.68 |
| ▸ | CTSL | P07711 | 9/20 | 0.68 |
| ▸ | CTSB | P07858 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239744 | 0.90 | GBA1 (0.63) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6238044 | 0.89 | GBA1 (0.62) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6239397 | 0.89 | GBA1 (0.62) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6235680 | 0.88 | MAPT (0.57) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6237209 | 0.87 | CTSK (0.67) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6238645 | 0.86 | GBA1 (0.51) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL8314339 | 0.84 | CTSS (0.63) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6239273 | 0.83 | GBA1 (0.53) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6238813 | 0.83 | CTSL (0.48) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6239305 | 0.83 | GBA1 (0.52) | CTSSCTSKCTSLCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |