Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.63 |
| ▸ | CTSK | P43235 | 11/20 | 0.63 |
| ▸ | CTSL | P07711 | 10/20 | 0.63 |
| ▸ | CTSB | P07858 | 9/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237944 | 0.90 | CTSK (0.49) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6236367 | 0.88 | CTSK (0.63) | CTSSCTSKCTSLCTSBPOLB | |
| SCHEMBL6238470 | 0.84 | CTSS (0.68) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6236029 | 0.81 | GPR119 (0.44) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6241614 | 0.77 | CTSK (0.76) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL15029661 | 0.76 | PIK3CB (0.65) | — | |
| SCHEMBL6239744 | 0.74 | GBA1 (0.63) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6239397 | 0.73 | GBA1 (0.62) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL6238044 | 0.73 | GBA1 (0.62) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL5255701 | 0.73 | CTSK (0.82) | CTSSCTSKCTSLCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |