Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 2/20 | 0.44 |
| ▸ | ARG2 | P78540 | 2/20 | 0.44 |
| ▸ | FDPS | P14324 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ODC1 | P11926 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235982 | 1.00 | ARG1 (0.44) | ARG1ARG2FDPSMEN1ALDH1A1 | |
| SCHEMBL28820015 | 0.91 | FDPS (0.47) | ARG1ARG2FDPSSMPD1FAAH | |
| SCHEMBL27538248 | 0.91 | FDPS (0.47) | ARG1ARG2FDPSSMPD1FAAH | |
| SCHEMBL29657696 | 0.86 | FDPS (0.47) | ARG1ARG2FDPSSMPD1CES2 | |
| SCHEMBL3806647 | 0.86 | FDPS (0.43) | ARG1ARG2FDPSMEN1ALDH1A1 | |
| SCHEMBL8173375 | 0.84 | FDPS (0.48) | ARG1ARG2FDPSSMPD1CES2 | |
| SCHEMBL6666220 | 0.82 | ARG2 (0.63) | ARG1ARG2FDPSMEN1ALDH1A1 | |
| SCHEMBL7465019 | 0.82 | ARG2 (0.63) | ARG1ARG2FDPSMEN1ALDH1A1 | |
| SCHEMBL27961818 | 0.82 | FDPS (0.50) | FDPSSMPD1CES2 | |
| Stearic Acid SCHEMBL27715155 | 0.82 | GPR84 (0.57) | MEN1ALDH1A1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1172354-B1 | Process for the preparation of (schiff bases of)alpha-alkyl-alpha-amino acid amides | DSM IP ASSETS BV (NL) | 2005-06-01 | — | — | EP | disclosed |
| US-6603043-B2 | Process for the preparation of (schiff bases of) α-alkyl-α-amino acid amides | DSM N.V. (NL) | 2003-08-05 | — | — | US | disclosed |
| US-20020072634-A1 | Process for the preparation of (schiff bases of) alpha-alkyl-alpha-amino acid amides | DSM IP ASSETS B.V. (NL) | 2002-06-13 | — | — | US | disclosed |
| EP-1172354-A2 | Process for the preparation of (schiff bases of)alpha-alkyl-alpha-amino acid amides | DSM N.V. (NL) | 2002-01-16 | — | — | EP | disclosed |