Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004610 | 0.93 | F2RL3 (0.57) | F2RL3EPHB4PIM1FYNPIM2 | |
| SCHEMBL1946067 | 0.89 | F2RL3 (0.52) | F2RL3EPHB4PIM1FYNPIM2 | |
| SCHEMBL625504 | 0.86 | PIM1 (0.56) | F2RL3PIM1PIM2FLT3 | |
| SCHEMBL623847 | 0.86 | F2RL3 (0.52) | F2RL3EPHB4PIM1MEN1KMT2A | |
| SCHEMBL624031 | 0.86 | F2RL3 (0.50) | F2RL3EPHB4PIM1FYNPIM2 | |
| SCHEMBL625205 | 0.85 | F2RL3 (0.53) | F2RL3EPHB4PIM1FYNVCP | |
| SCHEMBL623852 | 0.84 | FYN (0.42) | F2RL3EPHB4FYNPIM2 | |
| SCHEMBL623578 | 0.82 | F2RL3 (0.48) | F2RL3EPHB4PIM1MEN1POLB | |
| SCHEMBL2257601 | 0.82 | F2RL3 (0.55) | F2RL3MEN1KMT2AVCP | |
| SCHEMBL628029 | 0.82 | F2RL3 (0.49) | F2RL3KDM1APIM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |