Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628029 | 0.90 | F2RL3 (0.49) | F2RL3PIM1 | |
| SCHEMBL17004610 | 0.89 | F2RL3 (0.57) | F2RL3CNR2PIM1FYNVCP | |
| SCHEMBL623847 | 0.88 | F2RL3 (0.52) | F2RL3CNR2PIM1FYNVCP | |
| SCHEMBL623578 | 0.87 | F2RL3 (0.48) | F2RL3PIM1FYNVCPEPHB4 | |
| SCHEMBL624031 | 0.86 | F2RL3 (0.50) | F2RL3CNR2PIM1FYNVCP | |
| SCHEMBL623883 | 0.85 | F2RL3 (0.52) | F2RL3PIM1FYNVCPEPHB4 | |
| SCHEMBL1946067 | 0.85 | F2RL3 (0.52) | F2RL3CNR2PIM1FYNVCP | |
| SCHEMBL625204 | 0.82 | FYN (0.60) | PIM1FYN | |
| SCHEMBL2250766 | 0.80 | FYN (0.53) | F2RL3PIM1FYNVCP | |
| SCHEMBL625257 | 0.80 | FYN (0.47) | PIM1FYNVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |