Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759812 | 0.83 | MAOB (0.65) | FFAR1FFAR4PPARDPPARANR1H2 | |
| SCHEMBL28141293 | 0.82 | AKR1B1 (0.58) | FFAR1FFAR4PTPRCPTPN1AKR1B1 | |
| SCHEMBL3500758 | 0.81 | MAOB (0.63) | FFAR1FFAR4PTPN1MAOB | |
| SCHEMBL6237464 | 0.81 | FFAR1 (0.55) | FFAR1FFAR4NR1H2NR1H3RXRA | |
| SCHEMBL6239954 | 0.79 | NR1H4 (0.56) | FFAR1FFAR4NR1H2NR1H3MAOB | |
| SCHEMBL2552269 | 0.78 | FOLH1 (0.53) | FFAR1FFAR4PTPRCPTPN1AKR1B1 | |
| SCHEMBL6237724 | 0.78 | MAOB (0.64) | FFAR1FFAR4PPARDMAOB | |
| SCHEMBL6239053 | 0.77 | FFAR1 (0.75) | FFAR1FFAR4 | |
| Methane SCHEMBL10567951 | 0.77 | FOLH1 (0.52) | FFAR1FFAR4PTPRCPTPN1AKR1B1 | |
| SCHEMBL1066614 | 0.77 | FFAR1 (0.70) | FFAR1FFAR4AKR1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |