Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 8/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857028 | 0.82 | L3MBTL1 (0.62) | FFAR1FFAR4 | |
| SCHEMBL6239017 | 0.81 | FFAR1 (0.51) | FFAR1FFAR4RXRANR1H2NR1H3 | |
| SCHEMBL4759812 | 0.81 | MAOB (0.65) | FFAR1FFAR4NR1H4RXRANR1H2 | |
| SCHEMBL29782307 | 0.80 | CXCL8 (0.58) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL534254 | 0.80 | CXCL8 (0.58) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL3500758 | 0.79 | MAOB (0.63) | FFAR1FFAR4 | |
| Hydrochloric Acid SCHEMBL2530814 | 0.78 | CXCL8 (0.57) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL28141293 | 0.77 | AKR1B1 (0.58) | FFAR1FFAR4 | |
| SCHEMBL6239954 | 0.77 | NR1H4 (0.56) | FFAR1FFAR4NR1H4NR1H2NR1H3 | |
| SCHEMBL378766 | 0.76 | EPHX2 (0.54) | NR1H4RXRARXRBRXRGMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |