SCHEMBL7998071

SCHEMBL7998071

NC(=O)CC[C@H](N)C(=O)OC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.60
BLM P54132 1/20 0.60
PMP22 Q01453 1/20 0.60
KMT2A Q03164 1/20 0.60
GRIK1 P39086 8/20 0.42
GRIK2 Q13002 6/20 0.42
SLC1A1 P43005 3/20 0.42
GRIA4 P48058 2/20 0.42
GRIK3 Q13003 2/20 0.42
GRIK5 Q16478 2/20 0.42
GRM1 Q13255 2/20 0.42
GRM2 Q14416 2/20 0.42
SLC1A3 P43003 2/20 0.42
SLC1A2 P43004 2/20 0.42
GRM8 O00222 1/20 0.42
GRM6 O15303 1/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GSR P00390 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9452863 0.89 ALOX15 (0.48) ALOX15BLMPMP22KMT2AGRIK1
SCHEMBL2443865 0.88 KMT2A (0.68) ALOX15BLMPMP22KMT2AGRIK1
SCHEMBL693114 0.88 GRIK1 (0.44) ALOX15BLMPMP22KMT2AGRIK1
SCHEMBL9817851 0.88 GRIK1 (0.44) ALOX15BLMPMP22KMT2AGRIK1
SCHEMBL27574890 0.86 SLC1A1 (0.42) ALOX15BLMPMP22KMT2AGRIK1
SCHEMBL16054489 0.86 ALOX15 (0.43) ALOX15BLMPMP22KMT2AGRIK1
SCHEMBL6239265 0.84 GRIK1 (0.41) ALOX15BLMPMP22KMT2AGRIK1
SCHEMBL17559225 0.82 ALOX15 (0.42) ALOX15BLMPMP22KMT2ADPP4
SCHEMBL352342 0.82 ALOX15 (0.52) ALOX15BLMPMP22KMT2AGRIK1
SCHEMBL28571398 0.82 ALOX15 (0.52) ALOX15BLMPMP22KMT2AGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190241607-A1 COMPOSITIONS AND METHODS FOR DETECTION OF BETA N METHYLAMINO L ALANINE IN CU ZN SUPEROXIDE DISMUTASE 1 UNIV NORTH CAROLINA STATE (US) 2019-08-08 US disclosed
EP-3102611-A1 HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF Cangene Corporation (CA) 2016-12-14 EP disclosed
WO-2015113169-A1 HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF CNJ HOLDINGS, INC. (CA) 2015-08-06 WO disclosed
CN-101374942-A Method for purifying stem cell, embryonic cardiomyocyte and putative cardiomyocyte ASUBIO PHARMA CO LTD (JP) 2009-02-25 CN disclosed
EP-0514509-B1 COMPOSITION AND ITS PREPARATION PROCESS USING ANTIGEN CONJUGATED TO ENZYMATIC ACTIVITY FOR IMMUNOLOGICAL DIAGNOSIS AND CHAGAS' DISEASE IMMUNOLOGICAL DIAGNOSIS KITS, FOR INDIVIDUAL AND EPIDEMIOLOGICAL APPLICATION, BASED ON THAT COMPOSITION FUNDACAO OSWALDO CRUZ (BR) 2000-09-20 EP disclosed
WO-2000001720-A2 COMPOSITIONS AND METHODS FOR TREATING PAPILLOMAVIRUS-INFECTED CELLS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-01-13 WO disclosed
EP-0557406-A4 -G(G)-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS 1993-10-06 EP disclosed
EP-0557406-A1 GAMMA-TURN PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1993-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190241607-A1 COMPOSITIONS AND METHODS FOR DETECTION OF BETA N METHYLAMINO L ALANINE IN CU ZN SUPEROXIDE DISMUTASE 1 SOD1, SOD3, BCAT1 ALOX15 653/4885BLM 1280/4885PMP22 482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.