Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239381 | 0.95 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL8993599 | 0.76 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL8993514 | 0.76 | PTGS2 (0.52) | PTGS2 | |
| SCHEMBL3246525 | 0.75 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL8993504 | 0.74 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL8608632 | 0.74 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL4432809 | 0.73 | LMNA (0.50) | PTGS2 | |
| SCHEMBL23361312 | 0.72 | PTGS2 (0.58) | PTGS2 | |
| SCHEMBL29826462 | 0.72 | PTGS2 (0.58) | PTGS2 | |
| SCHEMBL8548523 | 0.72 | PTGS2 (0.65) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509217-A1 | MONOTHERAPY FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS WITH CYCLOOXYGENASE-2 (COX 2) INHIBITOR(S) | Pharmacia Corporation (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101441-A1 | MONOTHERAPY FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS WITH CYCLOOXYGENASE-2 (COX 2) INHIBITOR(S) | PHARMACIA CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |