Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1739665 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRATMTDP1 | |
| SCHEMBL28429440 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRATMTDP1 | |
| SCHEMBL6242110 | 0.79 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL1739669 | 0.78 | LMNA (0.52) | ALDH1A1CYP3A4TSHRATMTDP1 | |
| SCHEMBL6239130 | 0.78 | ALDH1A1 (0.40) | ALDH1A1CYP3A4TSHRATMTDP1 | |
| SCHEMBL1740099 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TSHRATMTDP1 | |
| SCHEMBL11735671 | 0.76 | MGAM (0.39) | ALDH1A1CYP3A4TSHRATMTDP1 | |
| SCHEMBL385349 | 0.75 | ELANE (0.43) | ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL6239399 | 0.75 | GABRP (0.45) | — | |
| SCHEMBL2945497 | 0.74 | LMNA (0.32) | ALDH1A1CYP3A4TSHRATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549669-A1 | TUMOR TARGETING AGENTS AND USES THEREOF | Karyon OY (FI) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004031221-A1 | TUMOR TARGETING AGENTS AND USES THEREOF | KARYON OY (FI) | 2004-04-15 | — | — | WO | disclosed |