Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.68 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.68 |
| ▸ | TDP2 | O95551 | 1/20 | 0.68 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.64 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.64 |
| ▸ | CDC25A | P30304 | 7/20 | 0.56 |
| ▸ | CDC25B | P30305 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MITF | O75030 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891344 | 0.85 | HKDC1 (0.70) | HKDC1TLR9TDP2PAX8HSP90AA1 | |
| SCHEMBL6240574 | 0.85 | TDP2 (0.55) | HKDC1TLR9TDP2PAX8HSP90AA1 | |
| SCHEMBL7957003 | 0.84 | HKDC1 (0.78) | HKDC1TLR9TDP2PAX8HSP90AA1 | |
| SCHEMBL7955400 | 0.81 | TDP2 (1.00) | HKDC1TLR9TDP2PAX8HSP90AA1 | |
| SCHEMBL6239508 | 0.79 | TDP2 (0.48) | HKDC1TLR9TDP2PAX8HSP90AA1 | |
| SCHEMBL6190569 | 0.78 | HSP90AA1 (1.00) | HKDC1TLR9TDP2PAX8HSP90AA1 | |
| SCHEMBL31087717 | 0.78 | HSP90AA1 (1.00) | HKDC1TLR9TDP2PAX8HSP90AA1 | |
| SCHEMBL7961611 | 0.77 | TDP2 (0.59) | HKDC1TLR9TDP2PAX8HSP90AA1 | |
| SCHEMBL134428 | 0.77 | HSP90AA1 (0.68) | HKDC1TLR9TDP2PAX8HSP90AA1 | |
| SCHEMBL31162649 | 0.77 | HSP90AA1 (0.68) | HKDC1TLR9TDP2PAX8HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016000-A1 | DERIVATIVES OF CYCLIC QUINONE AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2005-02-24 | — | — | WO | disclosed |
| US-20050032794-A1 | Diamine derivatives of quinone and uses thereof | CLINICAL DATA, INC. | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032794-A1 | Diamine derivatives of quinone and uses thereof | NQO1, DPYD, NQO2 | HKDC1 775/4885TLR9 2263/4885TDP2 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.