Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240574 | 0.93 | TDP2 (0.55) | TDP2PAX8HKDC1TLR9HSP90AA1 | |
| SCHEMBL6244227 | 0.81 | MAOA (0.48) | TDP2PAX8HKDC1TLR9HSP90AA1 | |
| SCHEMBL6241764 | 0.81 | MAOA (0.51) | TDP2PAX8HKDC1TLR9HSP90AA1 | |
| SCHEMBL6239428 | 0.79 | HKDC1 (0.68) | TDP2PAX8HKDC1TLR9HSP90AA1 | |
| SCHEMBL6240578 | 0.76 | HSP90AA1 (0.52) | TDP2PAX8HKDC1TLR9HSP90AA1 | |
| SCHEMBL6239513 | 0.75 | HSP90AA1 (0.50) | TDP2PAX8HKDC1TLR9HSP90AA1 | |
| SCHEMBL6240168 | 0.71 | HKDC1 (0.43) | TDP2PAX8HKDC1TLR9HSP90AA1 | |
| SCHEMBL6192892 | 0.70 | MAOA (0.52) | TDP2PAX8HKDC1TLR9HSP90AA1 | |
| SCHEMBL7957003 | 0.69 | HKDC1 (0.78) | TDP2PAX8HKDC1TLR9HSP90AA1 | |
| SCHEMBL10891344 | 0.67 | HKDC1 (0.70) | TDP2PAX8HKDC1TLR9HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016264-A2 | DIAMINE DERIVATIVES OF QUINONE AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2005-02-24 | — | — | WO | disclosed |